Argentine superstar Messi opened the scoring in the 27th minute and assisted on Suarez's first goal in the 68th minute for a 2-0 edge.

Israeli forward Tai Baribo scored twice for Philadelphia to give them the two goal advantage but Lionel Messi gave Miami hope with an 87th-minute free-kick before Venezuelan Segovia dramatically grabbed the point.

“[We need to] keep going. It's a complicated time,” Messi said in a post-match interview with Apple TV.

The Florida derby defeat leaves Miami with just one win from their last seven games in all competitions and they slip to sixth in the Eastern Conference with Orlando leapfrogging them.

The Argentine scored in the second half but Miami's defence was once again exposed as they fell to a fourth defeat in their last five games in all competitions -- a run which has seen them concede 14 goals.

Miami had lost their last three games, including a 5-1 aggregate defeat to the Vancouver Whitecaps in the Champions Cup semi-finals, but they got a much-needed morale boost with a comfortable Major League Soccer victory.

A dejected-looking Lionel Messi walked off the field in defeat on Wednesday after his Inter Miami team were exposed in emphatic fashion by a young Vancouver Whitecaps.

For Messi's Miami, the focus will turn to their bid for a first MLS Cup and their FIFA Club World Cup campaign.

Messi's impact was limited -- he was quickly closed down by Vancouver and was restricted to an optimistic long-range effort in the 29th minute which flew high over the bar.

A crowd of 60,614 turned out at Huntington Bank Field, the home of the NFL's Cleveland Browns, for the visit of Lionel Messi and friends and while the Argentine had a quiet game, Miami left with the points.

“No, yes in a joking tone we often talk, but he has those desires to play the World Cup next year too,” Suarez told Ovacion.

A club-record crowd of 62,358 packed into Soldier Field for the visit of Lionel Messi and his Inter team to witness a gutsy display from the home side.

Messi tucked the 84th minute spot kick into the corner to complete the comeback for Miami and earn them a place in the last four.

Too often Messi, who played the full game, was trying to create by himself while crowded out by Toronto defenders but did he test Johnson with a low shot in the 77th minute after working some space for himself.

A 57th-minute strike from Los Angeles-born El Salvador international Nathan Ordaz handed LAFC a precious advantage heading into next Wednesday's return leg in Florida.

Messi had missed Argentina's World Cup qualifiers in South America during the recent international window after picking up an adductor strain in Miami's most recent Major League Soccer game, a 2-1 win at Atlanta on March 16.

Veteran Haiti international Fafa Picault headed in the winning goal in the 89th minute to give Miami a precious victory that extended their unbeaten start to the season.

It marked the third straight game that Messi failed to feature for Miami after he did not travel to Houston for last week's 4-1 win in MLS before watching the 2-0 victory over Jamaica's Cavalier in the CONCACAF Champions Cup first-leg game on Thursday.

Luis Suarez scored a goal and assisted on three others to lead Inter Miami to a dominant 4-1 victory over the host Houston Dynamo on Sunday night.

Messi scored in the 1-0 first-leg win in icy Kansas City last week and it took him only 19 minutes to find the target at a much warmer Chase Stadium in Fort Lauderdale in the return.