Prostate Cancer
Vitamin B6 tied to better survival
Vitamin B6 is found in a range of foods, including beans, potatoes, bananas, meat, chicken, peanut butter and certain fish, like salmon and tuna.
Men with earlier-stage prostate cancer may have better survival odds if they get a little more than the recommended amount of vitamin B6 everyday, a new study suggests. The findings, reported in the American Journal of Clinical Nutrition, do not prove that vitamin B6 improves prostate cancer survival. But they do point to an association between survival and amounts of the vitamin that are readily attainable through a balanced diet. Researchers found that among 525 Swedish men with prostate cancer, the one-quarter with the highest B6 intakes were 29 percent less likely than those with the lowest intakes to die of the disease during the study period. Men in the former group averaged 2.2 to 2.9 milligrams of vitamin B6 per day, while those in the latter group got 1.3 to 1.9 milligrams daily. The recommended vitamin B6 intake for men age 50 and younger is 1.3 mg per day, while older men are encouraged to get 1.7 mg. The protective effect of B6 appeared confined to men whose tumors had not yet spread beyond the prostate at the time of diagnosis. When the researchers considered only these men, they found that those who got the most B6 had only 5 percent of the risk of dying as their counterparts with the lowest intakes of the vitamin. The results offer "exciting preliminary support" for dietary factors in long-term prostate cancer survival, according to lead researcher Dr. Julie L. Kasperzyk, a post-doctoral fellow at the Harvard School of Public Health in Boston. Vitamin B6 is found in a range of foods, including beans, potatoes, bananas, meat, chicken, peanut butter and certain fish, like salmon and tuna. It serves a variety of functions in the body — one being its role, together with other B vitamins, in DNA synthesis and repair. Cancer arises from the uncontrolled growth of genetically abnormal cells — which, in theory, means that the B vitamins could affect the development or spread of certain cancers. Overall, 42 percent of the men died of prostate cancer during the study period. The odds were lower, however, among those with the highest vitamin B6 intakes — although there was no evidence of protection among men diagnosed with advanced cancer. None of the other nutrients was linked to prostate cancer survival. Source: American Journal of Clinical Nutrition
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