Nadal, Murray breeze thru
Defending men's champion Murray celebrated the news that he's about to become a father again by reaching the second round while world number two and two-time champion Nadal secured his 850th career victory with a 6-1, 6-3, 6-2 demolition of Australia's John Millman.
The top seed and world number one downed Kazakh lucky loser Alexander Bublik 6-1, 6-4, 6-2, showing little sign of the hip problem which plagued him.
Murray next faces Dustin Brown, the man who knocked out Rafael Nadal two years ago.
Meanwhile, fresh from winning his 10th French Open title, Nadal is just the seventh player to reach the 850-win mark, joining Roger Federer, Jimmy Connors, Ivan Lendl, John McEnroe, Andre Agassi and Guillermo Vilas.
Nadal, seeded to face Murray in the semi-finals, will play Donald Young for a place in the last 32.
"I haven't had many matches on grass for the last few years, but I had some positive feelings," said Nadal who missed last year's tournament with a wrist injury.
Nick Kyrgios, who beat Nadal at Wimbledon in 2014, won't get another opportunity to repeat that shock.
The combustible 20th seeded Australian was 6-3, 6-4 down to France's Pierre-Hugues Herbert when he called it quits on Court Three after failing to shake off the hip injury which has plagued him in recent weeks.
Kei Nishikori, the Japanese ninth seed, beat Italy's Marco Cecchinato 6-2, 6-2, 6-0 in just 72 minutes.
Women's second seed Simona Halep, blasted off court in the French Open final by Jelena Ostapenko, downed New Zealand qualifier Marina Erakovic 6-4, 6-1.
Halep, a Wimbledon semi-finalist in 2014, next faces Brazil's Beatriz Haddad Maria.
Petra Kvitova downed Sweden's Johanna Larsson 6-3, 6-4.
Kvitova was playing just her eighth match since suffering a potentially career-ending hand injury fighting off a knife-wielding burglar at her home in December.
Former world number one Victoria Azarenka starts against Catherine Bellis of the United States and will be playing her first Grand Slam since taking time off after last year's French Open to have her first child Leo in December.
French Open winner Ostapenko, the 2014 Wimbledon junior champion, takes on Aliaksandra Sasnovich of Belarus.
Venus Williams marked her 20th Wimbledon anniversary with a 7-6 (9/7), 6-4 win against Belgium's Elise Mertens.
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